1. Abstract
Since the beginning of the pandemic, numerous skin manifestations associated with COVID-19 have been reported in the literature. However, phanerian manifestations remain rare. We report a case of rapid-onset of universal alopecia associated with nail involvement secondary to SARS COV 2 infection in a 46-year-old female patient, who subsequently developed a relapse after the COVID 19 vaccination despite continuing the treatment. The physiopathological mechanisms underlying the disorders in our patient remain unknown, making this virus even more mysterious and raising questions about the nature of its association with dermatologic, autoimmune, and autoinflammatory manifestations.