Clinical Review on Dyes Used in Chromoendoscopic Technique

Dr. Sarada Anepu, Prof. K.V. Ramana Murthy

 

¹Principal Investigator - DST WOS, AU College of Pharmaceutical Sciences, Andhra University, Visakhapatnam India

²Professor, AU College of Pharmaceutical Sciences, Andhra University, Visakhapatnam India

 

*Corresponding author: AU College of Pharmaceutical Sciences, Andhra University, Visakhapatnam India, E-mail: sarada.anepu38@gmail.com

 

Citation: Dr. Sarada Anepu, et al., (2020) Clinical Review on Dyes Used in Chromoendoscopic Technique. World J Gastroenterol Hepatol Endosc, 3(3);1-11.

 

Copyright: © 2020, Sarada A, This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

 

ABSTRACT

 

Chromoendoscopic technique dates to 1970, when various dyes were used on the tissue lining the GI tract to detect subtle lesions that are hard to detect using normal endoscopic imaging. Applied colour enhances tissue characterisation thus providing easier identification of pathological condition.Chromoendoscopic systems improve the identification of minute changes in the surface pattern by improving the contrast of raised and deepened areas. Based on the type of stain used different types of epithelia can be easily differentiated. This is particularly helpful in surveillance programmes aiming to detect dysplasia and pre-neoplastic lesions [e.g. in Barretts oesophagus (BO) or inflammatory bowel disease (IBD)] with the diagnostic yield of targeted smarterâ„¢ biopsies being superior to random biopsies, thus reducing the histopathologic workload and potentially offsetting the costs for additional procedure time. This review discusses in detail various stains equipment and drawbacks of chromoendoscopy.

 

KEYWORDS: Chromoendoscopy, Dye, Spray Catheters

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