Fenpyroximate Poisoning: A Mini Review

Abstract

Fenpyroximate Is An Acaricide That Acts By Inhibiting The Complex I Of The Mitochondria. It Is A White Crystalline Powder With Poor Solubility In Water. Fenpyroximate Is Absorbed From Gastrointestinal Tract Following Ingestion Then Metabolized And Eliminated With A Half-Life Of 8 To 49 Hours Depending On The Dose. In Acute Toxicity Fenpyroximate Can Cause Metabolic Acidosis, Gastrointestinal Irritation, Neurotoxicity And CNS Depression. There Is No Specific Antidote For Fenpyroximate, Treatment Is Symptomatic And Supportive. Decontamination Should Be Considered, Rinse Contaminated Eyes With Water Immediately, Do Not Induce Emesis. Activated Charcoal Should Be Considerable, Management Of Hypotension, Metabolic Acidosis Should Be Done Carefully And Monitored. Benzodiazepines May Prevent Neurotoxicity And Seizure. Further Studies Are Needed For More Accurate Diagnosis And Treatment.

• Fulltext Article