Dr. Haidar
Alsaedi
Department of Basic Science, Faculty of
Dentistry, Al-Qadisyah University, Iraq
*Corresponding
author: Department of Basic Science, Faculty of Dentistry, Al-Qadisyah
University, Iraq, Email: haider.k.abaas@gmail.com
Citation: Alsaedi H
(2020) Hypoglycemic Action of Barley in Diabetic Rats. Science World Current
Trends in Agriculture, 1(1);1-4
Copyright: © 2020,
Haidar Alsaedi, This is an open-access article distributed under the terms of
the Creative Commons Attribution 4.0 International License, which permits
unrestricted use, distribution and reproduction in any medium, provided the
original author and source are credited.
ABSTRACT
The present study was aimed to find out the
protective effect of whole barley grain administration on lipid peroxidation
(LPO), activities. of antioxidant. enzymes in erythrocytes and insulin gene
expression.of pancreas in streptozotocin (STZ)-Induced, diabetic rats.
Experimental diabetes, Single was triggered. Dose of the STZ injection (60
mg/kg, i.p.). The tissue measured the oxidative stress. LPO amount, reduced
content of glutathione (GSH) and enzymatic activities of Dismutase (SOD)
superoxide, catalase (CAT). The peroxidase glutathione of erythrocytes (GPx)
and glutathione reductase (GR). Blood rise, glucose, LPO level with Reduction
and decrease in GSH content. Those were enzymatic operations. Observed
distinguishing characteristics of monitoring rats for diabetes. Administration
oral of a grain for barley. Complete grain to this caused a significant 42
days. Reduction of degree of LPOs. Rats treated in STZ (Class IV) diabetic
control rats (group II).
KEYWORDS: Barley,
Streptozotocin (STZ), Diabetes meltus, Insulin