Methadone vs. Acetaminophen Codeine plus Clonidine, As Opioid Substitution Scheme: A Pilot Appraisal

ABSTRACT

INTRODUCTION

Substitution therapy is defined as the administration under medical supervision of a prescribed psychoactive substance – pharmacologically related to the one producing dependence – to people with substance dependence, for achieving defined treatment aims. Objective of the present evaluation was a comparison between methadone and acetaminophen codeine plus clonidine about management of opioid withdrawal symptoms in a group of non-western inpatient population.

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