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1. Abstract
All
bisphosphonates including zolindronic acid improve BMD in osteoporosis and decrease
risk of spine, hip and other non-vertebral fractures significantly. The purpose
of this study was to assess safety of zolindronic acid in osteoporosis in
Kashmiri population. This was a descriptive cross sectional study conducted in
tertiary care hospital of Kashmir valley. 77 pts were enrolled in the study
with documented osteoporosis who received 5 mg zolindronic acid infusion with
adequate prior hydration. All pts was followed for immediate adverse effects
following infusion. Mild symptoms did occur in the form of fever, arthralgias,
myalgias, muscle cramps and nausea. Majority of the symptoms subsided within
two to three days of infusion. Our observations conclude that zolindronic acid
is very much safe and fairly tolerated drug in osteoporosis.
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