K.
Gharbi*, M.A. Lkousse, Y. Ismail, J. Atmani, A. Elfarouki, A. Ait Errami, S.
Oubaha, Z. Samlani, K. Krati
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Department
of Gastroenterology, CHU Mohammed VI Marrakech, Morocco
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*Corresponding
author: Dr.
K. Gharbi, Department of Gastroenterology, CHU Mohammed VI
Marrakech, Morocco, E-mail: khalidgharbi@gmail.com
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Citation:Â Dr. K. Gharbi (2020)
Urea / Creatinine Ratio Predictor of the High or Low Origin of Melena:
Prospective Study. World J Gastroenterol Hepatol Endosc, 3(3);1-2
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Copyright: © 2020, Dr. K.
Gharbi, et al. This is an open-access article distributed
under the terms of the
Creative
Commons Attribution 4.0 International License, which permits unrestricted use,
distribution and reproduction in any medium, provided the original author and
source are credited.
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INTRODUCTION
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In
patients with Gastrointestinal (GI) bleeding, the source of bleeding is
uncertain in the absence of hematemesis. It is very interesting to find easily
accessible and non-invasive methods to differentiate various sources of GI
bleeding before performing a fibroscopy and colonoscopy. When patients present
with melaena, the first problem faced by the clinician is identifying the site
of bleeding. While most patients, if not all, presenting with haematemesis have
an upper gastrointestinal bleed, the same is not true of patients with melaena.
This is because the colour of blood in stool depends on how long the blood
remains in the gastrointestinal tract and not on the site of bleeding [1]. The
plasma urea:creatinine ratio (U:C ratio) has been reported to be significantly
higher in patients with upper gastrointestinal bleeding [1]. The purpose of the
present study was to prospectively evaluate this hypothesis and a U:C ratio of
36 was used as the discriminatory level [2-8].
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KEYWORDS:Â Gastrointestinal
hemorrhage, Melena, Urea, Creatinine