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Urea / Creatinine Ratio Predictor of the High or Low Origin of Melena: Prospective Study 1

World Journal of Gastroenterology, Hepatology and Endoscopy (ISSN-2766-788X)

Urea / Creatinine Ratio Predictor of the High or Low Origin of Melena: Prospective Study

K. Gharbi*, M.A. Lkousse, Y. Ismail, J. Atmani, A. Elfarouki, A. Ait Errami, S. Oubaha, Z. Samlani, K. Krati

 

Department of Gastroenterology, CHU Mohammed VI Marrakech, Morocco

 

*Corresponding author: Dr. K. Gharbi, Department of Gastroenterology, CHU Mohammed VI Marrakech, Morocco, E-mail: khalidgharbi@gmail.com

 

Citation: Dr. K. Gharbi (2020) Urea / Creatinine Ratio Predictor of the High or Low Origin of Melena: Prospective Study. World J Gastroenterol Hepatol Endosc, 3(3);1-2

 

Copyright: © 2020, Dr. K. Gharbi, et al. This is an open-access article distributed under the terms of the

Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

 

INTRODUCTION

 

In patients with Gastrointestinal (GI) bleeding, the source of bleeding is uncertain in the absence of hematemesis. It is very interesting to find easily accessible and non-invasive methods to differentiate various sources of GI bleeding before performing a fibroscopy and colonoscopy. When patients present with melaena, the first problem faced by the clinician is identifying the site of bleeding. While most patients, if not all, presenting with haematemesis have an upper gastrointestinal bleed, the same is not true of patients with melaena. This is because the colour of blood in stool depends on how long the blood remains in the gastrointestinal tract and not on the site of bleeding [1]. The plasma urea:creatinine ratio (U:C ratio) has been reported to be significantly higher in patients with upper gastrointestinal bleeding [1]. The purpose of the present study was to prospectively evaluate this hypothesis and a U:C ratio of 36 was used as the discriminatory level [2-8].

 

KEYWORDS: Gastrointestinal hemorrhage, Melena, Urea, Creatinine

 

Indexing Partners

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