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Open Access

Efficacy of Sulfadoxine Pyrimethamine as an Intermittent Preventive Treatment in Real-World Conditions on Parameters at Childbirth in Mali

Oumou Coulibaly, Mariam Tall, Abdou KB KAYENTAO, Mahamadou Dembele, Mahamadou Guindo, Sory I Diawara1 and Kassoum Kayentao

Article Type: Research Article | Release date: 28 Nov 2024

1. Abstract:Malaria during pregnancy is a major public health problem and is often associated with complications during pregnancy and childbirth. The aim of this study is to evaluate the effectiveness of intermittent preventive treatment with sulfadoxine pyrimethamine on delivery parameters.

Open Access

Therapeutic Algorithm for Duodenal Varices: A Case Series

Matsuda T, Ishikawa T, Sasaki R, Nishimura T, Iwamoto T, Takami T and Sakaida I

Article Type: Case Series | Release date: 29 Aug 2024

ABSTRACT Background: Duodenal varices cause fatal bleeding and are potentially life-threatening. Treatment guidelines for duodenal varices have not yet been established due to their low incidence. We report a case series of patients with duodenal varices admitted to our hospital between April 2012 and June 2017 and share our therapeutic algorithm for duodenal varices.

Open Access

Robotic Colonoscopy Endotics with Colon Wash: Two Performing Technologies in a Winning Combination

Cosentino F,  Rigante A, Barbera R,  Giuberti R, Tinelli R, Zanardi S

Article Type: Short Review | Release date: 28 Aug 2024

Colonoscopy is the standard method for CCR prevention, diagnosis, and treatment, but it is painful and highly de- pendent on quality of bowel preparation. This study describes the experience of the first 150 colonoscopies performed using the Endot- ics System at S. Giuseppe Hospital in Milan (Italy), demonstrating the effectiveness, diagnostic quality, and lack of pain even without sedation. Moreover, at the patient's request, robotic system was combined with Colon Wash technology, able to prepare the bowel in a comfortable and effective way without use of purgatives.

Open Access

Articular Cartilage: Can Articular Cartilage be Considered a Smart Material?

Zenon P Micha? S Bozena K

Article Type: Short Review | Release date: 27 Aug 2024

It has been shown that the “smart surface” of cartilage is highly hydrophilic when wet and hydrophobic when air-dry. The minimum surface energy of the bilayer was found to spread over a wide range of pH (6.5 to 9.5). The decreased number of bilayers changed the wettability and lowered the PL lubricant properties. In conclusion, a cartilage smart material can significantly react to changes pH and moisture.

Open Access

Effect of Obesity on Cardiovascular System: Literature Review

Sneineh MA 

Article Type: Review Article | Release date: 27 Aug 2024

Cardiovascular diseases (CVD) are the leading cause of global morbidity and mortality. Besides imparting a tremendous amount of human suffering, they also inflict huge direct and indirect financial costs on the worldwide society.

Open Access

Outcome of Stretta in a Tertiary Medical Center: ASafe and Effective Non-Surgical Option for Refractory GERD

Koldhekar A, Calderon L, XieM and Cai Q

Article Type: Original Article | Release date: 26 Aug 2024

BACKGROUND: Multiple treatment modalities exist to achieve symptom relief in Gastroesophageal Reflux Disorder (GERD), but there is mixed evidence for the efficacy of Stretta procedure.

Open Access

Wriggling Worms in The Gut During Endoscopy

Park J and Hye Oh E 

Article Type: Clinical Image | Release date: 26 Aug 2024

A 71-year-old man presented to the outpatient clinic with a 10-hour history of severe cramping epigastric pain. He reported that he ate sea eel sashimi a day ago. Six months prior, he underwent endoscopic retrograde cholangiopancreatography (ERCP) and cholecystecto- my for stones in the common bile duct and gallbladder. He had no other significant medical history. He reported approximately 2 oz of alcohol consumption every other day and no tobacco or illicit drug use.

Open Access

A Twisted Case of Anemia

Heinrich H and Bauerfeind P 

Article Type: Video Article | Release date: 26 Aug 2024

A 68-year-old patient was referred with asymptomatic iron deficiency anaemia with a haemoglobin of 8.6g/dl. History revealed no so signs of overt gastrointestinal bleeding. On clinical examination there were no signs of melena on DRE.

Open Access

Multiplexed Imaging Strategy to Distinguish Indeterminant Biliary Strictures: An Ex Vivo Study

Sturm MB Joshi BP Owens SR Seibel EJ3 Wang TD

Article Type: Research Article | Release date: 26 Aug 2024

ABSTRACT Introduction: Indeterminant biliary strictures can be either malignant or benign. Biliary intraepithelial neoplasia (BilIN) is the precursor lesion to cholangiocarcinoma, a deadly bile duct cancer. Current diagnostic methods are limited by inadequate amounts of cells and tissues collected.

Open Access

Factors Influencing Colorectal Cancer Screening Uptake among Saudi Adults; A Cross-Sectional Study

Alghamdi TH

Article Type: Case Report and Review | Release date: 26 Aug 2024

Abstract Introduction: Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. 1-5 The most commonly recognized cancers are colorectal, lung, and breast cancers with colorectal cancer (CRC) ranks as the third most common in terms of new cases (1.93 million cases) in the world and is also the second most common cancer-related deaths (935 000 deaths).

Open Access

Extended Right Hepatectomy with Partial Vena Cava Resection and Primary Vascular Reconstruction using Venous-venous Bypass for a Single Giant Metastasis from Colorectal Cancer: Case Report and Review of the Literature

Sergio Renato Pais-Costa, Guilherme Crispim Costa, Sergio Luiz Melo Araújo, Rafael De Negreiros Botan

Article Type: Case Report and Review | Release date: 26 Aug 2024

Hepatic Resection (HR) for Liver Metastasis from Colorectal Cancer (LMCRC) is considered golden standard treatment and additionally it is the single hope to attain a long-term survival in this scenario. 

Open Access

Long Haulers Effects of Covid-19 during Post-Covid-19

Khan I

Article Type: Review Article | Release date: 11 May 2024

Most of the covid patients recover, but some of them can have long term covid health effects which includes different systems of the body. The symptom can persist from weeks to years and can vary patient to patient.

Open Access

Recent Approach for Speeding up the Wound Healing

Abedi A

Article Type: Review Article | Release date: 11 May 2024

Healing wounds is an important physiological process in the body followed by trauma, burn injuries, post-surgery complications or different diseases that can damage the skin and tissues.

Open Access

Graphene Impurity in Biotechnolgical Products: Particle Size, Idrophilic Properties and Technological Implications: Hypotesys of Work

Luisetto M

Article Type: | Release date: 11 May 2024

Based on the fact that if present graphene in vials of nanolipids of biopharmaceutical the aspects must to be coloured the reported findings by some independet researcher of graphene like particle in viasl of m Rna covid-19 vaccine seem to suggest that this impurity can be present only inside the nanolipids. The production for this encapulated biotecnological product imply the mixing of an acqueos phases (mRna) with an lipidic phases (nanolipids).

Open Access

A Case of Sever Erythema Multiforme Following Covid-19 Vaccination: A Severe Cutaneous Reaction!

Chiheb S

Article Type: Cse Report | Release date: 30 Apr 2024

Vaccination against COVID-19 has brought hope for controlling this new pandemic. Several vaccines with different mechanisms of action have been developed.

Open Access

Cardiac Tamponade Revealing Systemic Lupus Erythematosos in Children: About Two Cases

Chkirate B

Article Type: Case Report | Release date: 30 Apr 2024

Initial cardiac tamponade revealing systemic lupus erythematosus (SLE) is rare and represents a diagnostic and therapeutic challenge. We report two cases presenting cardiac tamponade as the first manifestation of SLE, echocardiography confirmed cardiac tamponade, and biological assessment revealed markers of autoimmunity.

Open Access

Pemphigus Syphiliticus: Early Presentation of Congenital Syphilis

Hassani A

Article Type: Clinical Image | Release date: 30 Apr 2024

A newborn baby admitted for respiratory distress, from an unmonitored pregnancy, birth weight 3200g, 29-year-old mother, G2P1, with no particular history, height of 51.5cm and head circumference of 35.5cm.

Open Access

Severe Combined Immunodeficiency Revealed by Neonatal Erythroderma

Saghir S

Article Type: Clinical Image | Release date: 30 Apr 2024

Severe combined immunodeficiency (SCID) is a rare syndrome caused by a variety of genetic abnormalities and characterized by a lack of T-lymphocyte and B-lymphocyte function. It is a frequent cause of erythroderma in the neonatal period and should be considered in cases of severe erythroderma or erythroderma resistant to standard treatments.

Open Access

Classic Homocystinuria Revealed by a Stroke

Amar NB, Kabbaj K

Article Type: Case Report | Release date: 30 Apr 2024

Homocystinuria, by cystathionine beta-synthetase deficiency (CAS), is an autosomal recessive anomaly of sulfured amino acids catabolism.

Open Access

Amniotic Band Syndrome: A Rare and Little-Known Clinical Entity

Saghir S, Charaf FZ

Article Type: Clinical Image | Release date: 30 Apr 2024

Amniotic band disease is a group of complex congenital malformations, mainly affecting the limbs, the craniofacial region and the thoracoabdominal axis. There is exogenous theory: early rupture of the amnion leads to the formation of fibrous bridges, which are responsible of the strangulation; And endogenous theory favours a vascular origin, in which case the bridges have no causal role [1].

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