International Journal of Methods and Protocols primary research papers presenting or using new or improved methods in the biological sciences. It also publishes review papers devoted to methods used in the biological sciences. It primarily publishes in the areas of genetics and heredity, biochemistry, molecular biology, ecology, evolutionary biology, marine and freshwater biology and cell biology. This includes but is not limited to genome research, genome bioinformatics, computational biology, human molecular genetics, GWAS, developmental genetics, cancer genetics, neurogenetics, therapy of genetic disease, nucleic acids and proteins, gene regulation, chromatin and epigenetics, RNA and structural biology, protein-nucleic acid interaction, recombinant DNA expression, microarray technology, ribosomes and protein translation, targeted gene modification, plant and animal ecology, plant and animal evolution, micro and macro evolutionary processes, ecosystem ecology, conservation ecology, evolutionary ecology, theoretical ecology, and behavioural ecology. International Journal of Methods and Protocols papers describing novel software papers.  Such papers should describe the software and one application of it. We encourage authors to make their code available wherever possible.